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Abstract

Introduction: The surgical dentistry department of the CCTD in Casablanca is increasingly receiving cases of medication-related osteonecrosis of the jaws (MRONJ); however, there is a lack of epidemiological data in the department concerning aspects of these conditions. Therefor we proposed to conduct a descriptive cross-sectional study, the main objective of which is to draw up the epidemiological profile of cases of MRONJ in the Oral Surgical department and in the Oncology Department of the Ibn Rochd University Hospital in Casablanca. Methods: A descriptive cross-sectional prevalence study, lasting 2 years, was carried out in the surgical dentistry department of the CCTD and in the oncology department of the Ibn Rochd University Hospital in Casablanca. All patients on bisphosphonates or with a history of bisphosphonate treatment were included in the study. Data was collected on the basis of an anonymous self-administered questionnaire after obtaining the patient's consent. Statistical analysis was performed using SPSS version 22 software. Results: Our study population included 25 patients receiving BP treatment. The average age was 55 years old. 88% of patients were women. 64% of patients were receiving Zoledronic acid intravenously. MRONJ was diagnosed in 40% of the patients in our study. Mandibular localization was found in 70% of cases. 55.6% of patients had undergone dental extractions without preparation. Practitioners took a conservative approach to the treatment of MRONJ in 60% of patients. Conclusion: Several factors can promote or trigger the occurrence of MRONJ. They are both related to treatment with BP and to the patient. Given the frequency, the difficulty of management and the often reserved prognosis of this pathology, prevention and follow-up must occupy an important place in the management of patients

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